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In fact, DiNicolantonio et al.[15] found a 40% reduction in angina symptoms and a 65% decrease in dangerous heart rhythms, making it a valuable tool for improving quality of life in people with heart conditions

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In studies in mice, TMAO has been shown to cause atherosclerosis, the disease process that leads to cholesterol-clogged arteries

The HDACs are well known to control multiple vital biological processes such as cell proliferation, differentiation and development by binding to many transcription factors and transcription co-regulators (Haberland et al., 2009)